Wednesday 7 January 2015

What is Deoxyribonucleic acid or DNA

Understand Deoxyribonucleic acid or DNA. Click on the link to Watch the VIDEO explanation: Watch Video


DNA or Deoxyribonucleic acid is an information rich molecule that has laid the foundation of a new branch of science, Molecular Biology. Click on the links provided here. Here you can get the sense where DNA resides in a cell. A double stranded DNA is organised into chromosomes situated in the nucleus and the membrane bound nucleus is found in the cell. Structure of DNA is comparable to a twisted ladder. This double helical structure is proposed by James Watson and Francis Crick in 1953. A rotating wire frame model of Watson Crick DNA double helix is shown here. Main structures and features of DNA are shown here. The Sugar and Phosphate backbone is on the outside of double helix whereas Nitrogen basis are stacked inside. The two strand of helix are held together by specific base pairing. An Adenine molecule in one strand is paired with Thymine in other strand, Guanine is paired with Cytosine. One complete turn of a helix has ten base pair. The pattern of base pairing i.e. AT and GC is consistent with the known composition of DNA. Hydrogen bond are present between specific base pair. This animation demonstrates the mechanism of base pairing. Note the specific ways in which different Nitrogen base are paired. The AT pair is formed by two hydrogen bond while the GC pair has three hydrogen bonds. Some momentous events in the evolution of Heredity and Genetics are listed here. Click on the link for the event.

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